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KMID : 0376219730100010239
Chonnam Medical Journal
1973 Volume.10 No. 1 p.239 ~ p.251
Light and Electron Microscopic Studies on Cartilage Canal of Human Fetuses

Abstract
The light anThe light and electron microscopic observations were made on the structure of cartilage canal in epiphyseal cartilage.
The materials consisted of 42 human fetuses ranging from 50mm to 360mm crown rump length.
1. The initial appearance of cartilage canal of the humerus was first seen in the proximal epiphysis by 45mm, and in the distal epiphysis by 70mm. The cartilage canals of the femur were first seen in the proximal epiphysis by 60ncm, and in the distal epiphysis by 67mm.
2. Cartilage canals were observed to contain a number of thin walled blood vessels, and loose connective tissue. The vessels originated from perichondral vascular network at regular intervals and some of them communicated with those in the diaphysis.
3. There were various cellular and acellular components in the cartilage canal tissue. Endothelial cells in developing stage, contained various amount of granular endoplasmic reticulum, some mitochondria, and Golgi complex. Intercapillary mesenchymal cells bad prominent nucleus with nuclei, well developed granular endoplasmic reticulum with dilated cisternae, moderately developed Golgi complex, and some mitochondria. In the matrix of ground substance filamen tous materials were noted especially close to the cellular elements.
4. The surface cell of articular cartilage showed well developed Golgi area, moderate amount of granular endoplasmic reticulum, few mitochondria, small amount of glycogen particles, and filamentous materials, whereas in the deeper of the cartilage the cells contained more glycogen particles and filamentous materials than those in the surface region. The c artilagenous matrix consisted of ho:isogenous ground substance and fine filaments of about 30 to 100A in diameter. These fillaments showed no appreciable periodicity and formed a loose irregular network.
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